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The Factors that Affect Fertility (STDs)

A majority of sexually transmitted diseases (STDs), whether caused by bacteria, fungi, or viruses, are risk factors for infertility in both women and men (Pai et al., 2020). Common STDs such as gonorrhea, chlamydia, and Mycoplasma genitalium are associated with over 30 percent of fertility problems in women (Smolarczyk et al., 2021). Untreated STDs are a risk for inflammation and scarring of the reproductive organs, which affects the potency of the organs in reproductive use. STDs in men can cause inflammatory responses that affect the morphology, motility, and functioning of the sperms during development to maturation, with an impact on the ability of the sperms to swim (Pai et al., 2020). Untreated STDs in women also risk inflammation and scarring within the cervix, fallopian tube, and ovaries. This can lead to obstruction of the fallopian tube and peritoneal damage on the site of infection, with an impact on the victim’s fertility (Pai et al., 2020). Unchecked STDs are also linked to the development of pelvic inflammatory disease (PID). PID is a serious healthcare issue in women that leads to tubal factor infertility (TFI) due to damaged fallopian tubes, the uterus, and the inability of the eggs to move from the ovaries to the uterus (Smolarczyk et al., 2021).

Why Inflammatory Markers Rise in STD/PID

Inflammatory markers, majorly cytokines, C-reactive protein (CRP), and erythrocyte sedimentation rate (ESR) rise as a part of the immune response to infection and inflammation (Glaría & Valledor, 2020). STDs are the causal factors for PID, which is in itself an inflammatory infection of the female reproductive system (Smolarczyk et al., 2021). Both STDs and PID lead to an increased presence of pathogens, inflammation, and damage to the reproductive organs. This triggers an inflammatory response which includes an increased production of the inflammatory markers to counter the infection and repair the damaged tissue within the reproductive system. Persistent STD/PID infection and inflammation can lead to further production of the inflammatory markers with a risk of chronic inflammation and increased damage to the reproductive organs.

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Infections and Hematologic Disorders

The blood is prone to various infections and disorders which affect multiple body organs. This case analysis paper reviews a case scenario of a 67-year-old whose lab data shows that her hgb, hct, reticulocyte count, and serum B12 levels are low while mean corpuscle volume, plasma iron, and ferritin levels are high, folate, and TIBC are normal. The paper will explain the various hematologic disorders and infections related to the lab data outcomes.

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The Factors that Affect Fertility (STDs)

A majority of sexually transmitted diseases (STDs), whether caused by bacteria, fungi, or viruses, are risk factors for infertility in both women and men (Pai et al., 2020). Common STDs such as gonorrhea, chlamydia, and Mycoplasma genitalium are associated with over 30 percent of fertility problems in women (Smolarczyk et al., 2021). Untreated STDs are a risk for inflammation and scarring of the reproductive organs, which affects the potency of the organs in reproductive use. STDs in men can cause inflammatory responses that affect the morphology, motility, and functioning of the sperms during development to maturation, with an impact on the ability of the sperms to swim (Pai et al., 2020). Untreated STDs in women also risk inflammation and scarring within the cervix, fallopian tube, and ovaries. This can lead to obstruction of the fallopian tube and peritoneal damage on the site of infection, with an impact on the victim’s fertility (Pai et al., 2020). Unchecked STDs are also linked to the development of pelvic inflammatory disease (PID). PID is a serious healthcare issue in women that leads to tubal factor infertility (TFI) due to damaged fallopian tubes, the uterus, and the inability of the eggs to move from the ovaries to the uterus (Smolarczyk et al., 2021).

Why Inflammatory Markers Rise in STD/PID

Inflammatory markers, majorly cytokines, C-reactive protein (CRP), and erythrocyte sedimentation rate (ESR) rise as a part of the immune response to infection and inflammation (Glaría & Valledor, 2020). STDs are the causal factors for PID, which is in itself an inflammatory infection of the female reproductive system (Smolarczyk et al., 2021). Both STDs and PID lead to an increased presence of pathogens, inflammation, and damage to the reproductive organs. This triggers an inflammatory response which includes an increased production of the inflammatory markers to counter the infection and repair the damaged tissue within the reproductive system. Persistent STD/PID infection and inflammation can lead to further production of the inflammatory markers with a risk of chronic inflammation and increased damage to the reproductive organs.

 


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